A Bayesian hidden Markov model for detecting differentially methylated regions
DOI10.1111/BIOM.13000zbMATH Open1436.62578OpenAlexW2901166936WikidataQ93167870 ScholiaQ93167870MaRDI QIDQ5214527FDOQ5214527
Authors: Tieming Ji 
Publication date: 7 February 2020
Published in: Biometrics (Search for Journal in Brave)
Full work available at URL: https://doi.org/10.1111/biom.13000
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differentially methylated regionsBayesian hidden Markov modelsbisulfite sequencing experimentshyper-methylationhypo-methylation
Markov processes: estimation; hidden Markov models (62M05) Applications of statistics to biology and medical sciences; meta analysis (62P10) Protein sequences, DNA sequences (92D20)
Cited In (17)
- Assessing genome-wide significance for the detection of differentially methylated regions
- MethCP: differentially methylated region detection with change point models
- A hidden Markov model for identifying differentially methylated sites in bisulfite sequencing data
- Identifying intergenerational patterns of correlated methylation sites
- Bayesian inference supports a location and neighbour-dependent model of DNA methylation propagation at the MGMT gene promoter in lung tumours
- Comparing five statistical methods of differential methylation identification using bisulfite sequencing data
- Efficient detection and classification of epigenomic changes under multiple conditions
- Estimating DNA methylation levels by joint modeling of multiple methylation profiles from microarray data
- A novel statistical method for modeling covariate effects in bisulfite sequencing derived measures of DNA methylation
- Incorporating genomic annotation into a hidden Markov model for DNA methylation tiling array data
- A smoothed EM-algorithm for DNA methylation profiles from sequencing-based methods in cell lines or for a single cell type
- HMM-Fisher: identifying differential methylation using a hidden Markov model and Fisher's exact test
- HMM-DM: identifying differentially methylated regions using a hidden Markov model
- Modeling dependence in methylation patterns with application to ovarian carcinomas
- Bayesian Hidden Markov Modeling of Array CGH Data
- Integrating prior knowledge in multiple testing under dependence with applications to detecting differential DNA methylation
- An empirical Bayes approach for methylation differentiation at the single nucleotide resolution
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