Influence of the nuclear membrane, active transport, and cell shape on the Hes1 and p53-Mdm2 pathways: insights from spatio-temporal modelling
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Publication:1758081
DOI10.1007/s11538-012-9725-1zbMath1312.92021OpenAlexW2136821291WikidataQ51376079 ScholiaQ51376079MaRDI QIDQ1758081
Alan J. Terry, Dimitris P. Xirodimas, Marc Sturrock
Publication date: 7 November 2012
Published in: Bulletin of Mathematical Biology (Search for Journal in Brave)
Full work available at URL: https://doi.org/10.1007/s11538-012-9725-1
PDEs in connection with biology, chemistry and other natural sciences (35Q92) Biochemistry, molecular biology (92C40) Cell biology (92C37)
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Cites Work
- A dynamic P53-MDM2 model with time delay
- Models of genetic control by repression with time delays and spatial effects
- Interaction of spatial diffusion and delays in models of genetic control by repression
- Spatio-temporal modelling of the Hes1 and p53-Mdm2 intracellular signalling pathways
- Spatio-temporal modelling of the NF-\(\kappa\)B intracellular signalling pathway: the roles of diffusion, active transport, and cell geometry
- Oscillations and bistability in the stochastic model of p53 regulation
- Dissecting the dynamics of the Hes1 genetic oscillator
- Genetic control models with diffusion and delays
- Spatio-Temporal Modelling of the p53–mdm2 Oscillatory System
- Modelling transcriptional feedback loops: the role of Gro/TLE1 in Hes1 oscillations
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