Simultaneous inference: when should hypothesis testing problems be combined?

DOI10.1214/07-AOAS141zbMath1137.62010arXiv0803.3863OpenAlexW3098652185MaRDI QIDQ2482975

Efron, Bradley

Publication date: 30 April 2008

Published in: The Annals of Applied Statistics (Search for Journal in Brave)

Full work available at URL: https://arxiv.org/abs/0803.3863

zbMATH Keywords

enrichmentfalse discovery ratesseparate-class model

Mathematics Subject Classification ID

Nonparametric hypothesis testing (62G10) Parametric hypothesis testing (62F03) Bayesian inference (62F15) Foundations and philosophical topics in statistics (62A01)

Related Items (24)

Heteroscedasticity-Adjusted Ranking and Thresholding for Large-Scale Multiple Testing ⋮ On a Problem of Robbins ⋮ Weighted False Discovery Rate Control in Large-Scale Multiple Testing ⋮ A powerful FDR control procedure for multiple hypotheses ⋮ A double application of the Benjamini-Hochberg procedure for testing batched hypotheses ⋮ Reporting Bayes factors or probabilities to decision makers of unknown loss functions ⋮ Weighted multiple testing procedure for grouped hypotheses with \(k\)-FWER control ⋮ Bayesian variable selection using Knockoffs with applications to genomics ⋮ Rejoinder: ``Microarrays, empirical Bayes and the two-groups model ⋮ The future of indirect evidence ⋮ Power-enhanced multiple decision functions controlling family-wise error and false discovery rates ⋮ Genome-wide significance levels and weighted hypothesis testing ⋮ GAP: A General Framework for Information Pooling in Two-Sample Sparse Inference ⋮ Mutual fund performance: false discoveries, bias, and power ⋮ Weighted \(p\)-value procedures for controlling FDR of grouped hypotheses ⋮ Integrating Prior Knowledge in Multiple Testing under Dependence with Applications to Detecting Differential DNA Methylation ⋮ Controlling the false-discovery rate by procedures adapted to the length bias of RNA-seq ⋮ Empirical null and false discovery rate inference for exponential families ⋮ Empirical Bayes analysis of RNA sequencing experiments with auxiliary information ⋮ Covariate-Assisted Ranking and Screening for Large-Scale Two-Sample Inference ⋮ Adaptive \(p\)-value weighting with power optimality ⋮ Efficient Stratified Testing Procedure for a False Discovery Rate ⋮ Classes of multiple decision functions strongly controlling FWER and FDR ⋮ Interval estimation, point estimation, and null hypothesis significance testing calibrated by an estimated posterior probability of the null hypothesis

Uses Software

• GSA

Cites Work

• Unnamed Item
• GSA
• Random-set methods identify distinct aspects of the enrichment signal in gene-set analysis
• On testing the significance of sets of genes
• The control of the false discovery rate in multiple testing under dependency.
• Size, power and false discovery rates
• False discovery control with p-value weighting
• Linear Models and Empirical Bayes Methods for Assessing Differential Expression in Microarray Experiments
• Correlation and Large-Scale Simultaneous Significance Testing
• Testing Statistical Hypotheses
• Large-Scale Simultaneous Hypothesis Testing
• The Estimation of Prediction Error

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