Designed Extension of Studies Based on Conditional Power
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(92)- Inference of non-centrality parameter of a truncated non-central chi-squared distribution
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- Procedures for testing multiple endpoints in clinical trials: an overview
- Methodology and application of adaptive and sequential approaches in contemporary clinical trials
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- Asymptotic properties of maximum likelihood estimators with sample size recalculation
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- On the efficiency of adaptive designs for flexible interim decisions in clinical trials
- On design and inference for two-stage adaptive clinical trials with dependent data
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- Maximum type 1 error rate inflation in multiarmed clinical trials with adaptive interim sample size modifications
- An evaluation of inferential procedures for adaptive clinical trial designs with pre-specified rules for modifying the sample size
- Internal pilots for observational studies
- Sequential methods in multi-arm clinical trials
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- Adaptive group sequential designs for clinical trials: combining the advantages of adaptive and of classical group sequential approaches
- Monitoring Clinical Trials with Multiple Arms
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- An approach to the conditional error rate principle with nuisance parameters
- Benefit–Risk Evaluation of Multi-Stage Adaptive Designs
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- Are Flexible Designs Sound?
- Optimal Conditional Error Functions for the Control of Conditional Power
- Estimation of a Parameter and Its Exact Confidence Interval Following Sequential Sample Size Reestimation Trials
- Longitudinal clinical trials with adaptive choice of follow-up time
- Generalized Likelihood Ratio Statistics and Uncertainty Adjustments in Efficient Adaptive Design of Clinical Trials
- Development of Adaptive Group Sequential Procedure for Changing Sample Size
- Exact Confidence Bounds Following Adaptive Group Sequential Tests
- Data-Driven Analysis Strategies for Proportion Studies in Adaptive Group Sequential Test Designs
- THE ATTRACTIVENESS OF THE CONCEPT OF A PROSPECTIVELY DESIGNED TWO-STAGE CLINICAL TRIAL
- ESTIMATION FOLLOWING EXTENSION OF A STUDY ON THE BASIS OF CONDITIONAL POWER
- Improving the flexibility and efficiency of phase II designs for oncology trials
- Modification of Sample Size in Group Sequential Clinical Trials
- Adaptive Sample Size Calculations in Group Sequential Trials
- Interim Analysis and Sample Size Reassessment
- Interim design modifications in time-to-event studies
- Probabilistic foundation of confirmatory adaptive designs
- Adaptive multivariate global testing
- Novel Bayesian Adaptive Designs and Their Applications in Cancer Clinical Trials
- A note on the shape of sample size functions of optimal adaptive two-stage designs
- A comparison between two treatments in a clinical trial with an ethical allocation design
- p-Value calculation for multi-stage additive tests
- Discussion on “Second-Guessing Clinical Trial Designs” by Jonathan J. Shuster and Myron N. Chang
- Monitoring Continuous Long-Term Outcomes in Adaptive Designs
- Adaptive Design and Estimation in Randomized Clinical Trials with Correlated Observations
- The Influence of Biostatistics at the National Heart, Lung, and Blood Institute
- Sample size reassessment for a two-stage design controlling the false discovery rate
- Optimization of adaptive designs with respect to a performance score
- Single-arm phase II three-outcome designs with handling of over-running/under-running
- Blinded sample size recalculation in adaptive enrichment designs
- A covariate-adjusted adaptive design for two-stage clinical trials with survival data
- Two-stage randomized clinical trials with a right-censored endpoint: comparison of frequentist and Bayesian adaptive designs
- Adding experimental treatment arms to multi-arm multi-stage platform trials in progress
- A multi-arm multi-stage platform design that allows preplanned addition of arms while still controlling the family-wise error
- Point estimation, confidence intervals, and P-values for optimal adaptive two-stage designs with normal endpoints
- Sample size adaptation designs and efficiency comparison with group sequential designs
- A variational approach to optimal two-stage designs
- Conditional power and friends: the why and how of (un)planned, unblinded sample size recalculations in confirmatory trials
- Sample size re-estimation for covariate-adaptive randomized clinical trials
- Optimal planning of adaptive two-stage designs
- Optimal adaptive promising zone designs
- An additive boundary for group sequential designs with connection to conditional error
- Bayesian two-stage adaptive design in bioequivalence
- Confirmatory adaptive designs for clinical trials with multiple time-to-event outcomes in multi-state Markov models
- Group sequential designs for clinical trials when the maximum sample size is uncertain
- New results on optimal conditional error functions for adaptive two-stage designs
- Graph based, adaptive, multiarm, multiple endpoint, two-stage designs
- Adaptive sample size modification in clinical trials: start small then ask for more?
- Flexible selection of a single treatment incorporating short-term endpoint information in a phase II/III clinical trial
- Adaptive seamless designs with interim treatment selection: a case study in oncology
- Efficient testing of the biomarker positive and negative subgroups in a biomarker-stratified trial
- Sample size assessment and interim analysis strategies for survival trial designs with covariate-adaptive randomization
- Stepwise two-stage sample size adaptation
- Group sequential designs with prospectively planned rules for subpopulation enrichment
- Optimal flexible sample size design with robust power
- Maximum type I error rate inflation from sample size reassessment when investigators are blind to treatment labels
- Precision of maximum likelihood estimation in adaptive designs
- An objective re-evaluation of adaptive sample size re-estimation: commentary on ``Twenty-five years of confirmatory adaptive designs
- Twenty-five years of confirmatory adaptive designs: opportunities and pitfalls
- DOD-SSR: an adaptive seamless phase II/III design with dose optimization decision and sample size re-estimation
- Adaptive clinical trial designs with pre-specified rules for modifying the sample size: understanding efficient types of adaptation
- Planning future studies based on the conditional power of a meta-analysis
- A model-based conditional power assessment for decision making in randomized controlled trial studies
- A preplanned multi-stage platform trial for discovering multiple superior treatments with control of FWER and power
- A bi-endpoint expectation-maximisation algorithm for re-estimating sample size for the time-to-event endpoint under the blind condition
- Sample size adjustment in sequential multiple assignment randomized trials
- Improving the effectiveness of sample size re-estimation: an operating characteristic focused, hybrid frequentist-Bayesian approach
- Nonparametric adaptive enrichment designs using categorical surrogate data
- A comparison of methods for treatment selection in seamless phase II/III design
- A Bayesian adaptive design for two-stage clinical trials with survival data
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