Modeling HIV dynamics and antiviral response with consideration of time-varying drug exposures, adherence and phenotypic sensitivity
From MaRDI portal
Publication:1405284
DOI10.1016/S0025-5564(03)00058-0zbMath1030.92016WikidataQ44495120 ScholiaQ44495120MaRDI QIDQ1405284
Yangxin Huang, Susan L. Rosenkranz, Hulin Wu
Publication date: 25 August 2003
Published in: Mathematical Biosciences (Search for Journal in Brave)
HIV; Ordinary differential equations; Pharmacokinetics; Drug resistance; Adherence; Antiviral therapy; Clinical trial simulation
92C50: Medical applications (general)
Related Items
Mathematical Modeling of HIV-1 Infection and Drug Therapy, A Bayesian approach in differential equation dynamic models incorporating clinical factors and covariates, Viral dynamics of an HIV model with pulse antiretroviral therapy and adherence, Mathematical analysis of an HIV infection model including quiescent cells and periodic antiviral therapy, Statistical methods for HIV dynamic studies in AIDS clinical trials, Hierarchical Bayesian Methods for Estimation of Parameters in a Longitudinal HIV Dynamic System, Manifold-constrained Gaussian process inference for time-varying parameters in dynamic systems, An HIV infection model based on a vectored immunoprophylaxis experiment, Nonlinear and robust control strategy based on chemotherapy to minimize the HIV concentration in blood plasma, Mathematical analysis of an HIV model with impulsive antiretroviral drug doses, Permanence and extinction of a non-autonomous HIV-1 model with time delays, A dynamic Bayesian nonlinear mixed-effects model of HIV response incorporating medication adherence, drug resistance and covariates, Time-varying pharmacodynamics in a simple non-integer HIV infection model, A within-host virus model with multiple infected stages under time-varying environments, Monte Carlo estimates of natural variation in HIV infection, Parameter identifiability and estimation of HIV/AIDS dynamic models, On the modeling of long-term HIV-1 infection dynamics, Sieve estimation of constant and time-varying coefficients in nonlinear ordinary differential equation models by considering both numerical error and measurement error, Modeling long-term longitudinal HIV dynamics with application to an AIDS clinical study, Long-term HIV dynamic models incorporating drug adherence and resistance to treatment for prediction of virological responses, Threshold dynamics for an HIV model in periodic environments, Impact of antimicrobial usage on the transmission dynamics of antimicrobial resistant bacteria among pigs, Effect of cellular reservoirs and delays on the global dynamics of HIV, Explicitly accounting for antiretroviral drug uptake in theoretical HIV models predicts long-term failure of protease-only therapy, A multiscale model on hospital infections coupling macro and micro dynamics, A numerical efficient splitting method for the solution of HIV time periodic reaction-diffusion model having spatial heterogeneity, Machine learning for mathematical models of HCV kinetics during antiviral therapy, Stability analysis and memetic computation using differential evolution for in-host HIV model, Stochastic HIV model coupled with pharmacokinetics and drug adherence may explain intermittent viral blips, Complex patterns of viral load decay under antiretroviral therapy: influence of pharmacokinetics and intracellular delay, New insights into pharmacologic inhibition of pyroptotic cell death by necrosulfonamide: a PDE model, Optimal drug treatment regimens for HIV depend on adherence, Time periodic reaction-diffusion equations for modeling 2-LTR dynamics in HIV-infected patients, Spatially antiviral dynamics determines HCV in vivo replication and evolution, Modeling hepatitis C virus dynamics: liver regeneration and critical drug efficacy, Modeling within-host HIV-1 dynamics and the evolution of drug resistance: trade-offs between viral enzyme function and drug susceptibility, Oscillatory viral dynamics in a delayed HIV pathogenesis model, A delay-dependent model with HIV drug resistance during therapy, Stabilization of HIV/AIDS model by receding horizon control, Emergence of HIV-1 drug resistance during antiretroviral treatment, Models and estimation methods for clinical HIV-1 data, Piecewise HIV virus dynamic model with CD4\(^+\) T cell count-guided therapy: I, Modelling the effects of adherence to the HIV fusion inhibitor enfuvirtide, Comparison of particle swarm and bacterial foraging optimization algorithms for therapy planning in HIV/AIDS patients, DYNAMICS OF A NON-AUTONOMOUS HIV-1 INFECTION MODEL WITH DELAYS, THE DYNAMICS OF HIV MODELS WITH SWITCHING PARAMETERS AND PULSE CONTROL, Hierarchical Bayesian inference for HIV dynamic differential equation models incorporating multiple treatment factors, A Bayesian approach for estimating antiviral efficacy in HIV dynamic models
Cites Work
- HIV-1 infection and low steady state viral loads
- Stochastic modeling of the dynamics of \(CD4^ +\) \(T\)-cell infection by HIV and some Monte Carlo studies
- Dynamics of HIV infection of CD4\(^ +\) T cells
- Relationships between antiviral treatment effects and biphasic viral decay rates in modeling HIV dynamics
- Drug concentration heterogeneity facilitates the evolution of drug resistance
- Mathematical Analysis of HIV-1 Dynamics in Vivo
- Assessing antiviral potency of anti-HIV therapies in vivo by comparing viral decay rates in viral dynamic models
- Production of resistant HIV mutants during antiretroviral therapy
- Population HIV‐1 Dynamics In Vivo: Applicable Models and Inferential Tools for Virological Data from AIDS Clinical Trials
- Unnamed Item
- Unnamed Item
- Unnamed Item
