Real-time growth rate for general stochastic SIR epidemics on unclustered networks

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Publication:894285

DOI10.1016/J.MBS.2015.04.006zbMATH Open1326.92068arXiv1501.04824OpenAlexW2118699437WikidataQ41008698 ScholiaQ41008698MaRDI QIDQ894285FDOQ894285

Simon E. F. Spencer, Thomas House, Lorenzo Pellis

Publication date: 30 November 2015

Published in: Mathematical Biosciences (Search for Journal in Brave)

Abstract: Networks have become an important tool for infectious disease epidemiology. Most previous theoretical studies of transmission network models have either considered simple Markovian dynamics at the individual level, or have focused on the invasion threshold and final outcome of the epidemic. Here, we provide a general theory for early real-time behaviour of epidemics on large configuration model networks (i.e. static and locally unclustered), in particular focusing on the computation of the Malthusian parameter that describes the early exponential epidemic growth. Analytical, numerical and Monte-Carlo methods under a wide variety of Markovian and non-Markovian assumptions about the infectivity profile are presented. Numerous examples provide explicit quantification of the impact of the network structure on the temporal dynamics of the spread of infection and provide a benchmark for validating results of large scale simulations.


Full work available at URL: https://arxiv.org/abs/1501.04824




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