Emergence of HIV-1 drug resistance during antiretroviral treatment

DOI10.1007/s11538-007-9203-3zbMath1298.92053OpenAlexW2146089461WikidataQ51916706 ScholiaQ51916706MaRDI QIDQ2426347

Libin Rong, Alan S. Perelson, Zhilan Feng

Publication date: 22 April 2008

Published in: Bulletin of Mathematical Biology (Search for Journal in Brave)

Full work available at URL: https://doi.org/10.1007/s11538-007-9203-3

zbMATH Keywords

HIV-1 mutation antiretroviral therapy drug resistance viral kinetics adherence

Mathematics Subject Classification ID

Kinetics in biochemical problems (pharmacokinetics, enzyme kinetics, etc.) (92C45) Medical applications (general) (92C50)

Related Items (86)

Impact of antimicrobial usage on the transmission dynamics of antimicrobial resistant bacteria among pigs ⋮ A mathematical model for HIV treatment with time-varying antiretroviral therapy ⋮ Global dynamics of a two-strain HIV infection model with intracellular delay ⋮ Examining HIV progression mechanisms via mathematical approaches ⋮ Dynamics of an HIV model with multiple infection stages and treatment with different drug classes ⋮ Stochastic investigation of HIV infection and the emergence of drug resistance ⋮ Modeling HIV persistence, the latent reservoir, and viral blips ⋮ An HIV infection model based on a vectored immunoprophylaxis experiment ⋮ Piecewise virus-immune dynamic model with HIV-1 RNA-guided therapy ⋮ Analysis of HIV latent infection model with multiple infection stages and different drug classes ⋮ Within-host virus models with periodic antiviral therapy ⋮ Piecewise HIV virus dynamic model with CD4\(^+\) T cell count-guided therapy: I ⋮ The global dynamics in a wild-type and drug-resistant HIV infection model with saturated incidence ⋮ Asymptotic behavior of a stochastic delayed HIV-1 infection model with nonlinear incidence ⋮ A fractional-order model of HIV infection: Numerical solution and comparisons with data of patients ⋮ Stochastic HIV model coupled with pharmacokinetics and drug adherence may explain intermittent viral blips ⋮ DYNAMICS OF A NON-AUTONOMOUS HIV-1 INFECTION MODEL WITH DELAYS ⋮ Viral dynamics model with CTL immune response incorporating antiretroviral therapy ⋮ A within-host virus model with periodic multidrug therapy ⋮ Pulse HIV vaccination: feasibility for virus eradication and optimal vaccination schedule ⋮ Dynamic analysis of a fractional-order model for HIV with drug-resistance and CTL immune response ⋮ A within-host drug resistance model with continuous state-dependent viral strains ⋮ The role of backward mutations on the within-host dynamics of HIV-1 ⋮ Dynamics of an HIV infection model with two infection routes and evolutionary competition between two viral strains ⋮ Mathematical analysis of an HIV infection model including quiescent cells and periodic antiviral therapy ⋮ Modeling Pharmacodynamics on HIV Latent Infection: Choice of Drugs is Key to Successful Cure via Early Therapy ⋮ Towards a new combination therapy with vectored immunoprophylaxis for HIV: modeling ``Shock and kill strategy ⋮ Coupled within-host and between-host dynamics and evolution of virulence ⋮ Three-stage modeling of HIV infection and implications for antiretroviral therapy ⋮ Dynamics of an HIV infection model with two time delays ⋮ A multi-strain model with asymptomatic transmission: application to COVID-19 in the US ⋮ Periodic multidrug therapy in a within-host virus model ⋮ A delayed diffusive HBV model with nonlinear incidence and CTL immune response ⋮ Delayed model for HIV infection with drug effects ⋮ Mathematical analysis of an HIV model with impulsive antiretroviral drug doses ⋮ A model of HIV-1 infection with two time delays: mathematical analysis and comparison with patient data ⋮ Mathematical Modeling of HIV-1 Infection and Drug Therapy ⋮ Thresholds for extinction and proliferation in a stochastic tumour-immune model with pulsed comprehensive therapy ⋮ Environmental variability in a stochastic HIV infection model ⋮ Resistance to protease inhibitors in a model of HIV-1 infection with impulsive drug effects ⋮ Threshold virus dynamics with impulsive antiretroviral drug effects ⋮ Global stability for a delayed HIV-1 infection model with nonlinear incidence of infection ⋮ Global dynamics of a virus-immune system with virus-guided therapy and saturation growth of virus ⋮ Modeling within-host HIV-1 dynamics and the evolution of drug resistance: trade-offs between viral enzyme function and drug susceptibility ⋮ Analysis of a viral infection model with delayed nonlytic immune response ⋮ A fractional-order model of HIV infection with drug therapy effect ⋮ A multi-strain virus model with infected cell age structure: application to HIV ⋮ Complete classification of global dynamics of a virus model with immune responses ⋮ Permanence and extinction of a non-autonomous HIV-1 model with time delays ⋮ Analysis of HIV models with multiple target cell populations and general nonlinear rates of viral infection and cell death ⋮ Emerging disease dynamics in a model coupling within-host and between-host systems ⋮ Analysis of HIV models with two time delays ⋮ An HIV model with age-structured latently infected cells ⋮ Incubation periods under various anti-retroviral therapies in homogeneous mixing and age-structured dynamical models: a theoretical approach ⋮ Time-varying pharmacodynamics in a simple non-integer HIV infection model ⋮ Conflict and accord of optimal treatment strategies for HIV infection within and between hosts ⋮ A within-host virus model with multiple infected stages under time-varying environments ⋮ Mathematical analysis of an HIV latent infection model including both virus-to-cell infection and cell-to-cell transmission ⋮ Existence and Dynamics of Strains in a Nonlocal Reaction-Diffusion Model of Viral Evolution ⋮ HIV drug resistance: insights from mathematical modelling ⋮ Global dynamics and cost-effectiveness analysis of HIV pre-exposure prophylaxis and structured treatment interruptions based on a multi-scale model ⋮ The impact of cell regeneration on the dynamics of viral coinfection ⋮ Global dynamics for a drug-sensitive and drug-resistant mixed strains of HIV infection model with saturated incidence and distributed delays ⋮ A model incorporating combined RTIs and PIs therapy during early HIV-1 infection ⋮ Modeling the Effect of Reactive Oxygen Species and CTL Immune Response on HIV Dynamics ⋮ Modeling quasispecies and drug resistance in hepatitis C patients treated with a protease inhibitor ⋮ Impact of latently infected cells on strain archiving within HIV hosts ⋮ Dynamic programming approach to the numerical solution of optimal control with paradigm by a mathematical model for drug therapies of HIV/AIDS ⋮ Modeling HIV dynamics under combination therapy with inducers and antibodies ⋮ Within-host viral dynamics in a multi-compartmental environment ⋮ Models of impulsive culling of mosquitoes to interrupt transmission of West Nile Virus to birds ⋮ Estimation of the HIV-1 backward mutation rate from transmitted drug-resistant strains ⋮ Mathematical analysis of the transmission dynamics of brucellosis among bison ⋮ Minimizing \(\mathcal R_0\) for in-host virus model with periodic combination antiviral therapy ⋮ Modeling within-host viral dynamics: the role of CTL immune responses in the evolution of drug resistance ⋮ Threshold dynamics of a general delayed within-host viral infection model with humoral immunity and two modes of virus transmission ⋮ A piecewise model of virus-immune system with effector cell-guided therapy ⋮ The effects of CTL immune response on HIV infection model with potent therapy, latently infected cells and cell-to-cell viral transmission ⋮ A diffusive virus model with a fixed intracellular delay and combined drug treatments ⋮ A delayed HIV-1 model with virus waning term ⋮ Viral dynamics of an HIV model with pulse antiretroviral therapy and adherence ⋮ Persistence and global stability in a selection–mutation size-structured model ⋮ A delay-dependent model with HIV drug resistance during therapy ⋮ DYNAMICAL MODEL OF IN-HOST HIV INFECTION: WITH DRUG THERAPY AND MULTI VIRAL STRAINS ⋮ A class of virus dynamic model with inhibitory effect on the growth of uninfected T cells caused by infected T cells and its stability analysis ⋮ An in-host model of HIV incorporating latent infection and viral mutation

Cites Work

This page was built for publication: Emergence of HIV-1 drug resistance during antiretroviral treatment